Publication: Dummy Template Molecularly Imprinted Polymers as an Approach for Improved Efficiency for Analytical Applications: A Mini Review

BioVT is co-author of the mini-review "Dummy Template Molecularly Imprinted Polymers as an Approach for Improved Efficiency for Analytical Applications" published in Microchemical Journal.

Molecularly imprinted polymers (MIPs) are synthetic receptors that have been widely used as specific recognition elements in analysis, where they could selectively capture certain target analyte used for their preparation. MIP preparation encompasses the copolymerization of monomers and crosslinkers in the presence of the template or imprint molecule. Their preparation requires the use of large amounts of template molecules which should be removed thereafter leaving behind vacant cavities for analyte rebinding. Dummy template molecularly imprinted polymers (DMIPs) have recently evolved to enable the preparation of MIPs for selective capture of highly toxic, expensive, explosive, commercially unavailable target analytes, in addition to multiple analytes targeting. In this review, the different purposes for DMIP as well as the structural features of the dummy template are emphasized. Also, the major advantages of dummy template imprinting approach are discussed. The implication of DMIP on different analytical applications are highlighted discussing the benefits for using dummy templates in each.

A.A. Abella, Roland Ulber; Dummy Template Molecularly Imprinted Polymers as an Approach for Improved Efficiency for Analytical Applications; Microchemical Journal (2025) in press