Particle formulation
For various products, e.g. in the pharmaceutical, chemical and food industries, the formulation of solid particles with different substances is an important production step. At the Institute of Particle Process Engineering numerical simulation tools are used to develop new apparatus, to gain further information about particle motion and to optimize special particle processes, e.g. spheronization of cylindrical particles or coating of particles.
The current project in this area is called "Analysis of fluidization and shear conditions in rotor fluid beds under dry and wet conditions". The influence of fluid and particle shape on particle dynamics in a dense, sheared gas-solid flow is investigated. Granulation and coating are modeled with a CFD-DEM approach. Using the example of a rotor fluidized bed, detailed experimental investigations of the particle dynamics are carried out using a novel MPT measuring technique under dry and wet conditions (spraying liquids).
Contact: M. Sc. Fabian Krull
Research Areas
Research Projects
Hetero-Aggregation of fine particles in Supersonic flow for the tailor-made surface coating
September 15, 2021
Contact: Marc Weirich
Funding: DFG
Analysis of fluidization and shear conditions in rotor fluidized beds in dry and wet condition
August 20, 2019
Contact: Philipp Grohn
Funding: DFG
Completed Research Projects
Beschreibung der Mechanismen in der Herstellung kugelförmiger Granulatpartikel durch Sphäronisation
December 31, 2018
Contact: Dominik Weis
Funding: DFG
Recent Publications
Vafaeezadeh, M., Weber, K., Demchenko, A., Lösch, P., Breuninger, P., Lösch, A., Kopnarski, M., Antonyuk, S., Kleist, W., Thiel, W. R.: Janus bifunctional periodic mesoporous organosilica, Chemical Communications 58 (2022) 112-115, https://doi.org/10.1039/D1CC06086D
Grohn, P., Oesau, T., Heinrich, S., Antonyuk, S.: Investigation of the influence of wetting on the particle dynamics in a fluidized bed rotor granulator by MPT measurements and CFD-DEM simulations, Powder Technology 408 (2022) 117736 https://doi.org/10.1016/j.powtec.2022.117736
Grohn, P., Oesau, T., Heinrich, S., Antonyuk, S.: Investigation of the influence of impact velocity and liquid bridge volume on the maximum liquid bridge length, Advanced Powder Technology 33 (2022) 6, 103630, https://doi.org/10.1016/j.apt.2022.103630
Weis, D.: Beschreibung des Sphäronisationsprozesses von pharmazeutischen Pellets mittels numerischer Methoden. Dissertation, Schriftenreihe des Lehrstuhls für Mechanische Verfahrenstechnik der TU Kaiserslautern, (2021) Band 24, ISBN 978-3-95974-144-6
T. Oesau, P. Grohn, S. Pietsch-Braune, S. Antonyuk, S. Heinrich (2021): Novel approach for measurement of restitution coefficient by magnetic particle tracking, Advanced Powder Technology, https://doi.org/10.1016/j.apt.2021.11.014
Evers, M., Weis, D., Antonyuk, S., Thommes, M.: Particle movement in the spheronizer – Experimental investigations with respect to the toroidal and poloidal direction, Powder Technology 404 (2022) 117452, https://doi.org/10.1016/j.powtec.2022.117452
Vafaeezadeh, M., Weber, K., Demchenko, A., Lösch, P., Breuninger, P., Lösch, A., Kopnarski, M., Antonyuk, S., Kleist, W., Thiel, W. R.: Janus bifunctional periodic mesoporous organosilica, Chemical Communications 58 (2022) 112-115, https://doi.org/10.1039/D1CC06086D
Dominik Weis, Philipp Grohn, Maria Evers, Markus Thommes, Edwin García, Sergiy Antonyuk (2020): “Implementation of formation mechanisms in DEM simulation of the spheronization process of pharmaceutical pellets”, Powder Technology. https://doi.org/10.1016/j.powtec.2020.09.013
Philipp Grohn, Marius Lawall, Tobias Oesau, Stefan Heinrich, Sergiy Antonyuk (2020): “CFD-DEM Simulation of a Coating Process in a Fluidized Bed Rotor Granulator”, Processes 8 (9), S. 1090. https://doi.org/10.3390/pr8091090
Philipp Grohn, Dominik Weis, Markus Thommes, Stefan Heinrich, Sergiy Antonyuk (2020): “Contact behavior of MCC pellets depending on their water content”, Chemical Engineering & Technology 2020, https://doi.org/10.1002/ceat.201900517
Weis, D.; Krull, F.; Mathy, J.; Evers, M.; Thommes, M.; Antonyuk, S.: A contact model for the deformation behaviour of pharmaceutical pellets under cyclic loading, Advanced Powder Technology (2019), In Press, https://doi.org/10.1016/j.apt.2019.07.026
Weis, D.; Niesing, M.; Thommes, M.; Antonyuk, S.: DEM simulations of the mixing behavior in a spheronization process, Chemical Engineering Science 192 (2018), 803-815, https://doi.org/10.1016/j.ces.2018.07.057
Breuninger, P.; Weis, D.; Behrendt, I.; Grohn, P.; Krull, F.; Antonyuk, S.: CFD-DEM simulation of fine particles in a spouted bed apparatus with a Wurster tube, Particuology (2018), https://doi.org/10.1016/j.partic.2018.03.015
Weis, D.; Niesing, M.; Thommes, M.; Antonyuk, S.: Partikelkinematik in der Sphäronisation pharmazeutischer Pellets, Chemie Ingenieur Technik (2017),https://doi.org/10.1002/cite.201600154
Vafaeezadeh, M., Wilhelm, C., Breuninger, P., Ernst, S., Antonyuk, S. and W. R. Thiel: A Janus-type heterogeneous phase transfer catalyst for adipic acid synthesis, ChemCatChem (2020) https://doi.org/10.1002/cctc.202000140
M. Vafaeezadeh, P. Breuninger, P. Lösch, C. Wilhelm, S. Ernst, S. Antonyuk, W. Thiel: Janus Interphase Organic‐Inorganic Hybrid Materials: Novel Water‐Friendly Heterogeneous Catalysts, ChemCatChem (2019), https://doi.org/10.1002/cctc.201900147
Laboratory Equipment
Uniaxial compression/tension tester in MicroCT
Insitu measurement of deformation and breakage behaviour (force rage 1-500 N) in the microcomputed tomography (minimum voxel size 500 nm)
100 kHz Acoustic Levitator
Investigation of the evaporation of micro droplets at different airflows and air humidities
Spouted bed apparatus
In house developed apparatus for coating of very finde (Geldart C) particles
SEM
Optical analysis of the particle size, form and roughness
Triboindenter
Meaurements of the particle defor-mation behaviour depending on the temperature, particle roughness
Texture Analyser
Meaurements of the particle deformation behaviour depending on the temperature and air humidity and meaurements of particle friction coefficients
High speed cameras
Measurement of dynamic impact of particle / droplet
Simulation Tools
ANSYS CFX, ANSYS Fluent
OpenFOAM
LIGGGHTS / CFDEMcoupling
EDEM solutions